2.4M
XNAS Volume
High vol.+loss this week
XNAS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 8,750 | 135,675 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 8,750 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.36 per share. | 05 Mar 2025 | 3,594 | 132,081 (0%) | 0% | 1.4 | 4,888 | Common Stock |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.36 per share. | 05 Mar 2025 | 6,708 | 292,531 (1%) | 0% | 1.4 | 9,123 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 18,750 | 299,239 (1%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 18,750 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 8,750 | 99,027 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 8,750 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.36 per share. | 05 Mar 2025 | 3,594 | 95,433 (0%) | 0% | 1.4 | 4,888 | Common Stock |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 9,125 | 130,673 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 9,125 | 9,125 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.42 per share. | 04 Mar 2025 | 3,748 | 126,925 (0%) | 0% | 1.4 | 5,322 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 31,125 | 291,625 (1%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 31,125 | 31,125 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.42 per share. | 04 Mar 2025 | 11,136 | 280,489 (1%) | 0% | 1.4 | 15,813 | Common Stock |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 9,125 | 94,025 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 9,125 | 9,125 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.42 per share. | 04 Mar 2025 | 3,748 | 90,277 (0%) | 0% | 1.4 | 5,322 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 7,875 | 100,642 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.42 per share. | 04 Mar 2025 | 2,334 | 98,308 (0%) | 0% | 1.4 | 3,314 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 7,875 | 7,875 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 10,320 | 121,548 (0%) | 0% | 1.6 | 16,409 | Common Stock |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 7,875 | 15,750 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 17,250 | 51,750 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 7,875 | 114,618 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 17,250 | 131,868 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 23,750 | 243,953 (1%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 41,750 | 125,250 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 23,750 | 47,500 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 25,203 | 260,500 (1%) | 0% | 1.6 | 40,073 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 41,750 | 285,703 (1%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 8,327 | 84,900 (0%) | 0% | 1.6 | 13,240 | Common Stock |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 13,400 | 40,200 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,875 | 79,827 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,875 | 13,750 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 13,400 | 93,227 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 9,450 | 92,767 (0%) | 0% | 1.6 | 15,026 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,875 | 13,750 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 25,000 | 75,000 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,875 | 77,217 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 25,000 | 102,217 (0%) | 0% | 0 | Common Stock | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,375 | 19,125 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 5,000 | 10,000 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 4,672 | 38,433 (0%) | 0% | 1.6 | 7,428 | Common Stock |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 6,375 | 43,105 (0%) | 0% | 0 | Common Stock | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 5,000 | 36,730 (0%) | 0% | 0 | Common Stock | |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 01 Mar 2025 | 4,621 | 30,749 (0%) | 0% | 1.6 | 7,347 | Common Stock |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 11,250 | 35,370 (0%) | 0% | 0 | Common Stock | |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2025 | 11,250 | 33,750 | - | - | Restricted Stock Units (RSUs) | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 37,500 | 61,874 (0%) | 0% | 0 | Common Stock | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 11,250 | 33,750 | - | - | Restricted Stock Unit (RSU) | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 37,500 | 75,000 | - | - | Restricted Stock Unit (RSU) | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 28 Feb 2025 | 4,621 | 53,098 (0%) | 0% | 1.6 | 7,347 | Common Stock |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 11,250 | 57,719 (0%) | 0% | 0 | Common Stock | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.59 per share. | 28 Feb 2025 | 15,405 | 46,469 (0%) | 0% | 1.6 | 24,494 | Common Stock |
| Chung Jane | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2024 | 25,000 | 79,262 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2024 | 25,000 | 75,000 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.69 per share. | 01 Dec 2024 | 8,920 | 70,342 (0%) | 0% | 2.7 | 23,995 | Common Stock |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Sep 2024 | 37,500 | 112,500 | - | - | Restricted Stock Units (RSUs) | |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.95 per share. | 18 Sep 2024 | 13,380 | 24,120 (0%) | 0% | 4.0 | 52,851 | Common Stock |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Sep 2024 | 37,500 | 37,500 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2024 | 18,750 | 60,951 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2024 | 18,750 | 18,750 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.12 per share. | 09 Aug 2024 | 6,689 | 54,262 (0%) | 0% | 3.1 | 20,870 | Common Stock |
| Sukhi Jagpal | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2024 | 28,959 | 28,959 | - | - | Stock Option (Right to Buy) | |
| Sukhi Jagpal | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2024 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Leyman | Chief Business Dev. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jul 2024 | 100,000 | 100,000 | - | - | Restricted Stock Units (RSUs) | |
| Barbara Leyman | Chief Business Dev. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jul 2024 | 125,000 | 125,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Connie L. Matsui | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Joseph M. Lobacki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Jon Marc Wigginton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Heidi Hunter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 2,500 | 7,500 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 2,500 | 32,622 (0%) | 0% | 0 | Common Stock | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.74 per share. | 01 May 2024 | 892 | 31,730 (0%) | 0% | 3.7 | 3,336 | Common Stock |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.50 per share. | 11 Apr 2024 | 7,582 | 30,122 (0%) | 0% | 4.5 | 34,119 | Common Stock |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Apr 2024 | 21,250 | 42,500 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Apr 2024 | 21,250 | 37,704 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 8,750 | 109,843 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 8,750 | 8,750 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 51,000 | 51,000 | - | - | Restricted Stock Units (RSUs) | |
| Edward C. Albini | CFO AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 68,000 | 68,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.54 per share. | 05 Mar 2024 | 3,100 | 106,743 (0%) | 0% | 4.5 | 14,074 | Common Stock |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 174,000 | 174,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.54 per share. | 05 Mar 2024 | 6,690 | 220,203 (0%) | 0% | 4.5 | 30,373 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 18,750 | 226,893 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 18,750 | 18,750 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 130,500 | 130,500 | - | - | Restricted Stock Units (RSUs) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 38,000 | 38,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.54 per share. | 05 Mar 2024 | 3,108 | 72,952 (0%) | 0% | 4.5 | 14,110 | Common Stock |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 8,750 | 76,060 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 16,500 | 16,500 | - | - | Restricted Stock Units (RSUs) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 22,000 | 22,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2024 | 8,750 | 8,750 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 28,500 | 28,500 | - | - | Restricted Stock Units (RSUs) | |
| Jane Chung | PRESIDENT AND COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Jane Chung | PRESIDENT AND COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 100,000 | 100,000 | - | - | Restricted Stock Units (RSUs) | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 45,000 | 45,000 | - | - | Restricted Stock Units (RSUs) | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 25,500 | 25,500 | - | - | Restricted Stock Units (RSUs) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy Common Stock) | |
| Hans-Peter Gerber | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 45,000 | 45,000 | - | - | Restricted Stock Units (RSUs) | |
| Edward C. Albini | CFO AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 69,000 | 69,000 | - | - | Restricted Stock Units (RSUs) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 167,000 | 167,000 | - | - | Restricted Stock Units (RSUs) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2024 | 37,100 | 37,100 | - | - | Restricted Stock Units (RSUs) | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 9,125 | 104,565 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 9,125 | 18,250 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.79 per share. | 04 Mar 2024 | 3,472 | 101,093 (0%) | 0% | 4.8 | 16,631 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 31,125 | 219,248 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 31,125 | 62,250 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.79 per share. | 04 Mar 2024 | 11,105 | 208,143 (0%) | 0% | 4.8 | 53,193 | Common Stock |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 9,125 | 71,049 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 9,125 | 18,250 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.79 per share. | 04 Mar 2024 | 3,739 | 67,310 (0%) | 0% | 4.8 | 17,910 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 7,875 | 15,750 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.79 per share. | 04 Mar 2024 | 2,209 | 42,201 (0%) | 0% | 4.8 | 10,581 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2024 | 7,875 | 44,410 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 7,875 | 98,667 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 7,875 | 23,625 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.95 per share. | 01 Mar 2024 | 3,227 | 95,440 (0%) | 0% | 5.0 | 15,974 | Common Stock |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.95 per share. | 01 Mar 2024 | 8,559 | 188,123 (0%) | 0% | 4.9 | 42,367 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 23,750 | 196,682 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 23,750 | 71,250 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.95 per share. | 01 Mar 2024 | 2,511 | 61,924 (0%) | 0% | 4.9 | 12,429 | Common Stock |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 6,875 | 64,435 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 6,875 | 20,625 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | PRESIDENT AND COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.95 per share. | 01 Mar 2024 | 2,038 | 36,535 (0%) | 0% | 4.9 | 10,088 | Common Stock |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 6,875 | 38,573 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | PRESIDENT AND COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 6,875 | 20,625 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 5,000 | 18,503 (0%) | 0% | 0 | Common Stock | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 5,000 | 15,000 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | CHIEF TECH OP OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.95 per share. | 01 Mar 2024 | 2,049 | 16,454 (0%) | 0% | 5.0 | 10,143 | Common Stock |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2024 | 37,500 | 37,500 (0%) | 0% | 0 | Common Stock | |
| Anne Borgman | CHIEF MEDICAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.91 per share. | 29 Feb 2024 | 13,126 | 24,374 (0%) | 0% | 4.9 | 64,449 | Common Stock |
| Anne Borgman | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2024 | 37,500 | 112,500 | - | - | Restricted Stock Unit (RSU) | |
| Newell J. William | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.99 per share. | 29 Jan 2024 | 5,634 | 172,932 (0%) | 0% | 5.0 | 28,114 | Common Stock |
| A. Linda Fitzpatrick | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 8,250 | 60,940 (0%) | 0% | 0 | Common Stock | |
| Fitzpatrick A. Linda | CHIEF PEOPLE & COMM. OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 8,250 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | CHIEF PORT. STRAT & ALNCE OFCR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 2,500 | 15,303 (0%) | 0% | 0 | Common Stock | |
| Albini Edward C. | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 5,250 | 0 | - | - | Restricted Stock Unit (RSU) | |
| J. Newell William | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 13,750 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | CHIEF PORT. STRAT & ALNCE OFCR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.99 per share. | 29 Jan 2024 | 1,024 | 14,279 (0%) | 0% | 5.0 | 5,110 | Common Stock |
| Newell J. William | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 13,750 | 178,566 (0%) | 0% | 0 | Common Stock | |
| Vasquez Nicki | CHIEF PORT. STRAT & ALNCE OFCR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 2,500 | 0 | - | - | Restricted Stock Unit (RSU) | |
| A. Fitzpatrick Linda | CHIEF PEOPLE & COMM. OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.99 per share. | 29 Jan 2024 | 3,380 | 57,560 (0%) | 0% | 5.0 | 16,866 | Common Stock |
| C. Edward Albini | CFO AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.99 per share. | 29 Jan 2024 | 2,151 | 90,792 (0%) | 0% | 5.0 | 10,733 | Common Stock |
| Albini Edward C. | CFO AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2024 | 5,250 | 92,943 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | CHIEF PORT. STRAT & ALNCE OFCR | Sale of securities on an exchange or to another person at price $ 5.00 per share. | 29 Jan 2024 | 12,185 | 12,803 (0%) | 0% | 5 | 60,925 | Common Stock |
| Chung Jane | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 100,000 | 100,000 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Brunilda Shtylla | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 4.71 per share. | 28 Aug 2023 | 15,428 | 0 (0%) | 0% | 4.7 | 72,595 | Common Stock |
| Brunilda Shtylla | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 4.59 per share. | 25 Aug 2023 | 11,613 | 12,928 (0%) | 0% | 4.6 | 53,282 | Common Stock |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2023 | 18,750 | 37,500 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.22 per share. | 09 Aug 2023 | 6,483 | 31,698 (0%) | 0% | 4.2 | 27,358 | Common Stock |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2023 | 18,750 | 38,181 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jul 2023 | 3,250 | 26,111 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jul 2023 | 3,250 | 6,500 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.70 per share. | 12 Jul 2023 | 1,123 | 24,988 (0%) | 0% | 4.7 | 5,278 | Common Stock |
| Daniel H. Petree | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Jun 2023 | 18,409 | 3,856 (0%) | 0% | 0 | Common Stock | |
| Daniel H. Petree | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Jun 2023 | 18,409 | 18,601 (0%) | 0% | 0 | Common Stock | |
| Connie L. Matsui | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Joseph M. Lobacki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Jon Marc Wigginton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Heidi Hunter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Venkatesh Srinivasan | Chief Tech Op Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2023 | 10,000 | 10,000 | - | - | Restricted Stock Unit (RSU) | |
| Venkatesh Srinivasan | Chief Tech Op Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2023 | 7,500 | 7,500 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Apr 2023 | 3,750 | 101,664 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Apr 2023 | 3,750 | 7,500 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.40 per share. | 14 Apr 2023 | 1,296 | 100,368 (0%) | 0% | 4.4 | 5,702 | Common Stock |
| Anne Borgman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 150,000 | 150,000 | - | - | Restricted Stock Unit (RSU) | |
| Anne Borgman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 175,000 | 175,000 | - | - | Stock Option (right to buy Common Stock) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 47,000 | 47,000 | - | - | Stock Option (right to buy Common Stock) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 17,500 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,125 | 27,375 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,125 | 85,531 (0%) | 0% | - | Common Stock | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 94,281 (0%) | 0% | - | Common Stock | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 6,588 | 87,693 (0%) | 0% | 5.8 | 38,145 | Common Stock |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 31,500 | 31,500 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 18,750 | 37,500 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 31,125 | 163,312 (0%) | 0% | - | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 18,750 | 182,062 (0%) | 0% | - | Common Stock | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 17,246 | 164,816 (0%) | 0% | 5.8 | 99,854 | Common Stock |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 125,000 | 125,000 | - | - | Stock Option (right to buy Common Stock) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 95,000 | 95,000 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 31,125 | 93,375 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 40,000 | 40,000 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,750 | 29,250 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 12,500 | 25,000 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,750 | 93,131 (0%) | 0% | - | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 12,500 | 105,631 (0%) | 0% | - | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 7,717 | 97,914 (0%) | 0% | 5.8 | 44,681 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 50,000 | 50,000 | - | - | Stock Option (right to buy Common Stock) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 27,500 | 27,500 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,125 | 27,375 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 17,500 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 9,125 | 50,335 (0%) | 0% | - | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 59,085 (0%) | 0% | - | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 6,395 | 52,690 (0%) | 0% | 5.8 | 37,027 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 40,000 | 40,000 | - | - | Stock Option (right to buy Common Stock) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 40,000 | 40,000 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 6,222 | 40,827 (0%) | 0% | 5.8 | 36,025 | Common Stock |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 47,049 (0%) | 0% | - | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 7,875 | 38,299 (0%) | 0% | - | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 8,750 | 17,500 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 7,875 | 23,625 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 7,875 | 23,625 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Jane Chung | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 3,211 | 19,431 (0%) | 0% | 5.8 | 18,592 | Common Stock |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 7,875 | 22,642 (0%) | 0% | - | Common Stock | |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 27,500 | 27,500 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 35,000 | 35,000 | - | - | Stock Option (right to buy Common Stock) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 6,750 | 22,351 (0%) | 0% | - | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 5,500 | 27,851 (0%) | 0% | - | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 4,990 | 22,861 (0%) | 0% | 5.8 | 28,892 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 25,000 | 25,000 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 6,750 | 20,250 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 5,500 | 11,000 | - | - | Restricted Stock Unit (RSU) | |
| Brunilda Shtylla | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 6,750 | 24,702 (0%) | 0% | - | Common Stock | |
| Brunilda Shtylla | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 4,375 | 29,077 (0%) | 0% | - | Common Stock | |
| Brunilda Shtylla | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.79 per share. | 03 Mar 2023 | 4,536 | 25,541 (0%) | 0% | 5.8 | 26,263 | Common Stock |
| Brunilda Shtylla | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 40,000 | 40,000 | - | - | Stock Option (right to buy Common Stock) | |
| Brunilda Shtylla | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 27,500 | 27,500 | - | - | Restricted Stock Unit (RSU) | |
| Brunilda Shtylla | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 6,750 | 20,250 | - | - | Restricted Stock Unit (RSU) | |
| Brunilda Shtylla | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2023 | 4,375 | 8,750 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Feb 2023 | 45,698 | 0 | - | - | Stock Option (right to buy) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 13 Feb 2023 | 45,698 | 76,406 (0%) | 0% | 5.8 | 265,414 | Common Stock |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 2,140 | 30,708 (0%) | 0% | 7.5 | 16,050 | Common Stock |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 5,250 | 32,848 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 5,250 | 5,250 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 5,600 | 132,187 (0%) | 0% | 7.5 | 42,000 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 13,750 | 137,787 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 13,750 | 13,750 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 2,140 | 83,381 (0%) | 0% | 7.5 | 16,050 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 5,250 | 5,250 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 5,250 | 85,521 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 3,364 | 41,210 (0%) | 0% | 7.5 | 25,230 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 8,250 | 44,574 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 8,250 | 8,250 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 4,500 | 32,259 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 1,835 | 30,424 (0%) | 0% | 7.5 | 13,763 | Common Stock |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 4,500 | 4,500 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 2,500 | 16,620 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2023 | 2,500 | 2,500 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.50 per share. | 27 Jan 2023 | 1,019 | 15,601 (0%) | 0% | 7.5 | 7,643 | Common Stock |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2022 | 18,750 | 56,250 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.60 per share. | 09 Aug 2022 | 6,483 | 14,767 (0%) | 0% | 6.6 | 42,788 | Common Stock |
| Jane Chung | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2022 | 18,750 | 21,250 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jul 2022 | 3,250 | 15,243 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jul 2022 | 3,250 | 9,750 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.08 per share. | 12 Jul 2022 | 1,123 | 14,120 (0%) | 0% | 6.1 | 6,828 | Common Stock |
| Connie L. Matsui | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Shalini Sharp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Joseph M. Lobacki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Jon Marc Wigginton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Heidi Hunter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.26 per share. | 14 Apr 2022 | 1,296 | 80,271 (0%) | 0% | 7.3 | 9,409 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Apr 2022 | 3,750 | 11,250 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Apr 2022 | 3,750 | 81,567 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Purchase of securities on an exchange or from another person at price $ 7.75 per share. | 14 Mar 2022 | 10,000 | 116,525 (0%) | 0% | 7.8 | 77,508 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 4,355 | 37,736 (0%) | 0% | 8.2 | 35,580 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 12,500 | 37,500 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 39,000 | 39,000 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 52,000 | 52,000 | - | - | Stock Option (right to buy Common Stock) | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 12,500 | 42,091 (0%) | 0% | - | Common Stock | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 30,743 (0%) | 0% | - | Common Stock | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 3,145 | 27,598 (0%) | 0% | 8.2 | 25,695 | Common Stock |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 42,000 | 42,000 | - | - | Stock Option (right to buy Common Stock) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 36,500 | 36,500 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 26,250 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 18,750 | 56,250 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 18,750 | 119,943 (0%) | 0% | - | Common Stock | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 6,483 | 113,460 (0%) | 0% | 8.2 | 52,966 | Common Stock |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 166,000 | 166,000 | - | - | Stock Option (right to buy Common Stock) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 124,500 | 124,500 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 12,500 | 37,500 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 12,500 | 82,095 (0%) | 0% | - | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 4,278 | 77,817 (0%) | 0% | 8.2 | 34,951 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 52,000 | 52,000 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 39,000 | 39,000 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 42,000 | 42,000 | - | - | Stock Option (right to buy Common Stock) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 39,296 (0%) | 0% | - | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 2,972 | 36,324 (0%) | 0% | 8.2 | 24,281 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 26,250 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 36,500 | 36,500 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 30,959 (0%) | 0% | - | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 42,000 | 42,000 | - | - | Stock Option (right to buy Common Stock) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 31,500 | 31,500 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 8,750 | 26,250 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 3,200 | 27,759 (0%) | 0% | 8.2 | 26,144 | Common Stock |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 31,500 | 31,500 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 42,000 | 42,000 | - | - | Stock Option (right to buy) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 27,000 | 27,000 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 5,500 | 14,246 (0%) | 0% | - | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 04 Mar 2022 | 2,253 | 11,993 (0%) | 0% | 8.2 | 18,407 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2022 | 36,000 | 36,000 | - | - | Stock Option (right to buy Common Stock) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 5,500 | 16,500 | - | - | Restricted Stock Unit (RSU) | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 4,545 | 0 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 2,617 | 0 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 578 | 0 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 873 | 0 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 2,124 | 0 | - | - | Stock Option | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2022 | 3,540 | 0 | - | - | Stock Option | |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 08 Feb 2022 | 578 | 15,728 (0%) | 0% | 5.8 | 3,358 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 08 Feb 2022 | 2,617 | 15,150 (0%) | 0% | 4.4 | 11,410 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 08 Feb 2022 | 4,545 | 12,533 (0%) | 0% | 4.4 | 19,816 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 08 Feb 2022 | 873 | 16,601 (0%) | 0% | 5.8 | 5,072 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 08 Feb 2022 | 2,124 | 18,725 (0%) | 0% | 5.8 | 12,340 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 08 Feb 2022 | 3,540 | 22,265 (0%) | 0% | 5.8 | 20,567 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 10,500 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 31,742 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 2,151 | 29,591 (0%) | 0% | 10.4 | 22,349 | Common Stock |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 10,500 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 24,144 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 2,151 | 21,993 (0%) | 0% | 10.4 | 22,349 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 13,750 | 106,471 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 13,750 | 27,500 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 5,278 | 101,193 (0%) | 0% | 10.4 | 54,838 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 10,500 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 5,250 | 71,746 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 2,151 | 69,595 (0%) | 0% | 10.4 | 22,349 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 3,380 | 30,546 (0%) | 0% | 10.4 | 35,118 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 8,250 | 33,926 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 8,250 | 16,500 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 4,500 | 24,053 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 4,500 | 9,000 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 1,844 | 22,209 (0%) | 0% | 10.4 | 19,159 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 2,500 | 9,770 (0%) | 0% | 0 | Common Stock | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2022 | 2,500 | 5,000 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.39 per share. | 29 Jan 2022 | 1,024 | 8,746 (0%) | 0% | 10.4 | 10,639 | Common Stock |
| Heidi Hunter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2021 | 9,884 | 9,884 | - | - | Stock Option (right to buy Common Stock) | |
| Heidi Hunter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2021 | 24,000 | 24,000 | - | - | Stock Option (right to buy Common Stock) | |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 2,976 | 26,492 (0%) | 0% | 19.2 | 57,228 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 8,609 | 29,468 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 8,609 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 7,174 | 21,374 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 7,174 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 2,480 | 18,894 (0%) | 0% | 19.2 | 47,690 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 25,253 | 0 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 13,219 | 92,721 (0%) | 0% | 19.2 | 254,201 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 25,253 | 105,940 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Sep 2021 | 104,662 | 104,662 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Sep 2021 | 104,662 | 80,687 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 3,810 | 66,496 (0%) | 0% | 19.2 | 73,266 | Common Stock |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 11,019 | 70,306 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 11,019 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 7,576 | 28,295 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 7,576 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 2,619 | 25,676 (0%) | 0% | 19.2 | 50,363 | Common Stock |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 8,609 | 22,529 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 8,609 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 2,976 | 19,553 (0%) | 0% | 19.2 | 57,228 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.23 per share. | 24 Sep 2021 | 2,063 | 11,176 (0%) | 0% | 19.2 | 39,671 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 5,969 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Sale of securities on an exchange or to another person at price $ 18.62 per share. | 24 Sep 2021 | 3,906 | 7,270 (0%) | 0% | 18.6 | 72,724 | Common Stock |
| Nicki Vasquez | Chief Port. Strat & Alnce Ofcr | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Sep 2021 | 5,969 | 13,239 (0%) | 0% | 0 | Common Stock | |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2021 | 75,000 | 75,000 | - | - | Restricted Stock Unit (RSU) | |
| Jane Chung | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2021 | 160,000 | 160,000 | - | - | Stock Option (right to buy) | |
| Connie L. Matsui | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Shalini Sharp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Joseph M. Lobacki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Jon Marc Wigginton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 18,500 | 18,500 | - | - | Stock Option (right to buy) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Apr 2021 | 20,000 | 20,000 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Pres. Rsrch & Cf. Sctific Ofcr | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Apr 2021 | 15,000 | 15,000 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 60,000 | 60,000 | - | - | Stock Option (right to buy Common Stock) | |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 35,000 | 35,000 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy Common Stock) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 200,000 | 200,000 | - | - | Stock Option (right to buy Common Stock) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 75,000 | 75,000 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 60,000 | 60,000 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 35,000 | 35,000 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy Common Stock) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 35,000 | 35,000 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy Common Stock) | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 15,750 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 2,107 | 20,859 (0%) | 0% | 22.1 | 46,670 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 22,966 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 2,126 | 14,200 (0%) | 0% | 22.2 | 47,091 | Common Stock |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 16,326 (0%) | 0% | 0 | Common Stock | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 15,750 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 7,061 | 185,349 (0%) | 0% | 22.1 | 156,401 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 13,750 | 192,410 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 13,750 | 41,250 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 2,080 | 59,287 (0%) | 0% | 22.2 | 46,072 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 61,367 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 5,250 | 15,750 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 8,250 | 24,750 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 3,147 | 20,719 (0%) | 0% | 22.1 | 69,706 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 8,250 | 23,866 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 4,500 | 15,765 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.15 per share. | 29 Jan 2021 | 1,845 | 13,920 (0%) | 0% | 22.2 | 40,867 | Common Stock |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jan 2021 | 4,500 | 13,500 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jan 2021 | 2,393 | 4 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 26.10 per share. | 26 Jan 2021 | 165 | 56,117 (0%) | 0% | 26.1 | 4,306 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 25.68 per share. | 26 Jan 2021 | 2,228 | 56,282 (0%) | 0% | 25.7 | 57,222 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 26 Jan 2021 | 2,393 | 58,510 (0%) | 0% | 4.4 | 10,433 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 26 Jan 2021 | 4,132 | 7,988 (0%) | 0% | 4.4 | 18,016 | Common Stock |
| Daniel H. Petree | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jan 2021 | 4,132 | 0 | - | - | Stock Option (right to buy Common Stock) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jan 2021 | 1,652 | 0 | - | - | Stock Option (right to buy) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 19 Jan 2021 | 1,652 | 15,616 (0%) | 0% | 4.4 | 7,203 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 14 Jan 2021 | 19,405 | 56,117 (0%) | 0% | 4.4 | 84,606 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jan 2021 | 19,405 | 0 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 28 Dec 2020 | 2,393 | 39,105 (0%) | 0% | 4.4 | 10,433 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2020 | 2,393 | 2,397 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.37 per share. | 28 Dec 2020 | 2,393 | 36,712 (0%) | 0% | 22.4 | 53,530 | Common Stock |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 10 Dec 2020 | 56,327 | 56,327 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 10 Dec 2020 | 118,735 | 0 (0%) | 0% | 0 | Common Stock | |
| Jon Marc Wigginton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Nov 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.01 per share. | 27 Nov 2020 | 2,393 | 36,712 (0%) | 0% | 17.0 | 40,713 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Nov 2020 | 2,393 | 4,790 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 27 Nov 2020 | 2,393 | 39,105 (0%) | 0% | 4.4 | 10,433 | Common Stock |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 09 Nov 2020 | 118,735 | 118,735 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 09 Nov 2020 | 560,053 | 0 (0%) | 2% | 0 | Common Stock | |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 05 Nov 2020 | 16,751 | 36,712 (0%) | 0% | 15 | 251,265 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Nov 2020 | 16,751 | 7,183 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 05 Nov 2020 | 16,751 | 53,463 (0%) | 0% | 4.4 | 73,034 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Oct 2020 | 9,182 | 23,934 | - | - | Employee Stock Option (right to buy) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.36 per share. | 05 Oct 2020 | 9,182 | 36,712 (0%) | 0% | 4.4 | 40,034 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 2,976 | 17,716 (0%) | 0% | 10.3 | 30,653 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 8,609 | 20,692 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 8,609 | 8,609 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 2,480 | 11,076 (0%) | 0% | 10.3 | 25,544 | Common Stock |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 7,174 | 7,174 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 7,174 | 13,556 (0%) | 0% | 0 | Common Stock | |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 25,252 | 25,253 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 13,219 | 178,660 (0%) | 0% | 10.3 | 136,156 | Common Stock |
| William J. Newell | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 25,252 | 191,879 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 3,810 | 23,999 (0%) | 0% | 10.3 | 39,243 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 6,887 | 0 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 11,019 | 27,809 (0%) | 0% | 0 | Common Stock | |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 11,019 | 11,019 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 10.26 per share. | 25 Sep 2020 | 975 | 27,530 (0%) | 0% | 10.3 | 10,007 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 2,381 | 28,505 (0%) | 0% | 10.3 | 24,524 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 6,887 | 30,886 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 2,619 | 13,964 (0%) | 0% | 10.3 | 26,976 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 7,576 | 16,583 (0%) | 0% | 0 | Common Stock | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 7,576 | 7,576 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 8,609 | 14,241 (0%) | 0% | 0 | Common Stock | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 8,609 | 8,609 | - | - | Restricted Stock Unit (RSU) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.30 per share. | 25 Sep 2020 | 2,976 | 11,265 (0%) | 0% | 10.3 | 30,653 | Common Stock |
| John G. Freund | Director | Sale of securities on an exchange or to another person at price $ 12.00 per share. | 18 Sep 2020 | 400,000 | 560,053 (2%) | 1% | 12 | 4,800,000 | Common Stock |
| John G. Freund | Director | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 11 Sep 2020 | 500,000 | 960,053 (4%) | 2% | 10 | 5,000,000 | Common Stock |
| Trevor Hallam | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.04 per share. | 26 Aug 2020 | 975 | 16,790 (0%) | 0% | 9.0 | 8,818 | Common Stock |
| John G. Freund | Director | Sale of securities on an exchange or to another person at price $ 8.72 per share. | 19 Aug 2020 | 500,000 | 1,460,053 (6%) | 2% | 8.7 | 4,360,000 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 8.06 per share. | 27 Jul 2020 | 975 | 17,765 (0%) | 0% | 8.1 | 7,858 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 8.02 per share. | 26 Jun 2020 | 975 | 18,740 (0%) | 0% | 8.0 | 7,818 | Common Stock |
| Connie L. Matsui | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Shalini Sharp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Daniel H. Petree | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Joseph M. Lobacki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2020 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 26 May 2020 | 975 | 19,715 (0%) | 0% | 10.0 | 9,753 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 7.75 per share. | 14 May 2020 | 6,451 | 12,083 (0%) | 0% | 7.7 | 49,995 | Common Stock |
| William J. Newell | Director, CEO | Purchase of securities on an exchange or from another person at price $ 7.75 per share. | 14 May 2020 | 64,516 | 166,627 (0%) | 0% | 7.8 | 499,999 | Common Stock |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Purchase of securities on an exchange or from another person at price $ 7.75 per share. | 14 May 2020 | 3,225 | 9,007 (0%) | 0% | 7.8 | 24,994 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 11.00 per share. | 27 Apr 2020 | 2 | 20,690 (0%) | - | 11 | 22 | Common Stocck |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 9.42 per share. | 27 Apr 2020 | 973 | 20,692 (0%) | 0% | 9.4 | 9,161 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 9.70 per share. | 26 Mar 2020 | 975 | 21,665 (0%) | 0% | 9.7 | 9,453 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 10.47 per share. | 26 Feb 2020 | 975 | 22,640 (0%) | 0% | 10.5 | 10,207 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 47,500 | 47,500 | - | - | Stock Option (right to buy Common Stock) | |
| Alan H. Auerbach | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 21,000 | 21,000 | - | - | Restricted Stock Unit (RSU) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 47,500 | 47,500 | - | - | Stock Option (right to buy Common Stock) | |
| Edward C. Albini | CFO and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 21,000 | 21,000 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 55,000 | 55,000 | - | - | Restricted Stock Unit (RSU) | |
| William J. Newell | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 125,000 | 125,000 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Chief Science Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 47,500 | 47,500 | - | - | Stock Option (right to buy Common Stock) | |
| Trevor Hallam | Chief Science Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 21,000 | 21,000 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 33,000 | 33,000 | - | - | Restricted Stock Unit (RSU) | |
| Linda A. Fitzpatrick | Chief People & Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 66,250 | 66,250 | - | - | Stock Option (right to buy Common Stock) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 41,250 | 41,250 | - | - | Stock Option (right to buy Common Stock) | |
| Shabbir T. Anik | Chief Technical Ops. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2020 | 18,000 | 18,000 | - | - | Restricted Stock Unit (RSU) | |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 10.51 per share. | 27 Jan 2020 | 975 | 23,615 (0%) | 0% | 10.5 | 10,250 | Common Stock |
| James P. Panek | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 11.08 per share. | 26 Dec 2019 | 975 | 24,590 (0%) | 0% | 11.1 | 10,802 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 10.68 per share. | 26 Nov 2019 | 975 | 25,565 (0%) | 0% | 10.7 | 10,410 | Common Stock |
| Trevor Hallam | Chief Science Officer | Sale of securities on an exchange or to another person at price $ 9.98 per share. | 28 Oct 2019 | 975 | 26,540 (0%) | 0% | 10.0 | 9,726 | Common Stock |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Sep 2019 | 8,608 | 8,608 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Sep 2019 | 8,608 | 17,218 | - | - | Restricted Stock Unit (RSU) | |
| Alan H. Auerbach | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.74 per share. | 26 Sep 2019 | 2,976 | 5,632 (0%) | 0% | 9.7 | 28,986 | Common Stock |
| Edward C. Albini | CFO and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Sep 2019 | 7,174 | 8,862 (0%) | 0% | 0 | Common Stock |